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Studies indicate that medications like Ozempic can lead to significant weight loss, with some individuals experiencing reductions of up to 15% of their body weight
HbA 1c was also significantly reduced versus empagliflozin at 52 weeks using the treatment policy estimand, and at 26 and 52 weeks when assessed by the trial product estimand, which assumed that patients remained on treatment without rescue medication use [15]
Dose increases and higher doses raise the chance of GI intolerance
Nausea was the most common adverse event, significantly higher in the GLP-1RA group compared to placebo
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